BOTOX PARTIES all the rage, and Retin-A still setting the
standard in the battle against wrinkles, it was only a matter of
time before the cosmetics industry launched its counter attack.
Two new heavy-hitters have bounded onto the scene and are rapidly
gaining market share in this very fickle beauty business.
No-needle wrinkle relaxing?
PERHAPS the most commercially
viable Botox alternative, acetyl-hexapeptide (trade name Argireline),
developed by Spanish company Centerchem (www.centerchem.com),
is showing promise as a less toxic, much less invasive alternative
to the controversial injections.
According to the company's web site, Argireline
works through a unique mechanism which relaxes facial tension leading
to a reduction in superficial facial lines and wrinkles with regular
use. Argireline has been shown to moderate excessive catecholamine
(neurotransmitters that are believed to cause the formation of the
expressions leading to lines) release.
That's the claim. The result? It may not be as
effective as Botox in relaxing expression lines, but it doesn't
require a needle either. Whether this truly works as claimed remains
to be seen, though many companies using the compound cite the study
in the International Journal of Cosmetic Science (vol. 24,
no. 5, October 2002, p. 303) as proof that the compound works. The
study used a 10 per cent concentration in an oil/water emulsion.
The results showed reduced wrinkle depth up to 30 per cent upon
30 days treatment.
So if the idea of being injected with botulinum
neurotoxin sounds bit too scary and a bit too pricey, then products
touting acetyl hexapeptide may well be worth a try. There are lots
of options available, in all price categories.
How do you choose what's right for you? According
to beauty advisers in the know, the best bet is to go for a formula
that has the optimum concentration (around the 10 per cent mark)
and look for other, more traditional wrinkle-fighting ingredients
like antioxidants (Vitamins A, C, and E) in the mix, and few to
no irritants like SD alcohol.
Some products of note include the following.
Zia Natural Skincare Ultimate Day Renewal (containing acetyl-hexapeptide-3)
Desert Essence Age Reversal Face Serum (and Cream)
$29·99 (1·0 oz)
$79 (0·5 oz)
Bioque Serum XL
$85 (1·0 oz)
Crème de Vie
$112 (1·7 oz)
DDF Wrinkle Relax (also contains
palmitoyl pentapeptide, described in the next section)
$75 (0·5 oz)
DDF Anti-wrinkle Eye Renewal Treatment
$48 (0·5 oz treatment, included in kit)
Clair Lipo-Tox from Eudora International
$150 (0·5 oz)
BTX Double Action Gel
$38 (1·0 oz)